1. Identification
a. what does this name mean? Who named/discovered it?
Varicella(chicken pox) Zoster(shingles) late eighteenth century Herberden established a way to differentiate between the two diseases.(poc marks caused by VZV and those caused by smallpox) 1888- suggested by Von Bokay that chickenpox and herpes zoster were due to the same agent. Weller and Stoddard isolated the virus from chicken pox and zoster, then connecting the two, and found that they are both from the same virus.
b. What causes the disease?
Common contagious childhood disease. Vaccine made in 1994. If adults have the disease as a child, they are more vunerable to more serious complications later on. Such as shingles.
c. Has the disease changed over time? Mutations?
The investigation or the contributions of the VZV tk or DNA polmerase to antiviral drug resistance and their impacts on the structures of the viral proteins indicated specific patterns of cross-resistance and highlighted important differences. Havent become drug resistant to the vaccine. But antiviral drug resistance is an emerging problem.
d. Can you identify any phylogenies?
e. Do any other organisms carry or suffer from it?
No, only humans
2. Demographics a. Is it associated with any particular region of the world? Why?
Varicella occurs worldwide. In temperate climates, Varicella tends to be a childhood diesease. with at peak incidence during late winter and early spring. In tropical climates, infection tends to occur at older ages, resulting in higher susceptibility among adults than in temperate climates. Vaccine is used in United States, Austrailla, Canade, Costa Rica, Dominican republic, Germany, Mexico, Quatar, Spain, South Korea, Switezerland, United Arab Emirates and Urguary.
b. How many people has it affected?
most affected in US. over 1 million. Millions affected worldwide.
c. Is everyone equally vunerable, or does it target particular catagories of people? why?
(see question a) -people with weak immune systems. -Additionally, exposure to herpes zoster poses a risk for varicella infeciton in susceptable travelers although localized herpes zoster has been shown to be much less infectious than varicella. Travelers at higher risk for varicella disease are pregnent women without a history of disease or infeciton.
3. Impact
a. How has the disease impacted the course of history? Give an example.
The disease hasn't dramatically altered the course of history. Soon after the disease was discovered a vaccine was found. This disease didn't change the course of history.
b. How is the disease currently affeciting society? Now that we have a vaccine, the disease is much less prominent. People still get it as children, but now we know how to handle it, and it isnt a problem at all.
Sources Cited
"Historical Background." Virus. Web. 03 Mar. 2012. <http://virus.stanford.edu/herpes/History.html>. Andrei, G., and D. Topalis. "American Society for MicrobiologyJournal of Virology." Drug-Resistant Varicella-Zoster Virus Mutants. American Society for Microbiology, 20 Oct. 2011. Web. 03 Mar. 2012. <http://jvi.asm.org/content/86/5/2641.abstract>. Ehrlich, Steven D. "Varicella-zoster Virus." University of Maryland Medical Center. University of Maryland Medical Center, 2011. Web. 03 Mar. 2012. <http://www.umm.edu/altmed/articles/varicella-zoster-000080.htm>. Harriman, Kathleen Gilberto F. Chavez H., and Gilberto F. Chavez. "Chapter 3Infectious Diseases Related To Travel." Varicella (Chickenpox). Disease Control and Prevention, 1 July 2011. Web. 03 Mar. 2012. http://wwwnc.cdc.gov/travel/yellowbook/2012/chapter-3-infectious-diseases-related-to-travel/varicella-chickenpox.htm.
a. what does this name mean? Who named/discovered it?
Varicella(chicken pox) Zoster(shingles) late eighteenth century Herberden established a way to differentiate between the two diseases.(poc marks caused by VZV and those caused by smallpox) 1888- suggested by Von Bokay that chickenpox and herpes zoster were due to the same agent. Weller and Stoddard isolated the virus from chicken pox and zoster, then connecting the two, and found that they are both from the same virus.
b. What causes the disease?
Common contagious childhood disease. Vaccine made in 1994. If adults have the disease as a child, they are more vunerable to more serious complications later on. Such as shingles.
c. Has the disease changed over time? Mutations?
The investigation or the contributions of the VZV tk or DNA polmerase to antiviral drug resistance and their impacts on the structures of the viral proteins indicated specific patterns of cross-resistance and highlighted important differences. Havent become drug resistant to the vaccine. But antiviral drug resistance is an emerging problem.
d. Can you identify any phylogenies?
e. Do any other organisms carry or suffer from it?
No, only humans
2. Demographics a. Is it associated with any particular region of the world? Why?
Varicella occurs worldwide. In temperate climates, Varicella tends to be a childhood diesease. with at peak incidence during late winter and early spring. In tropical climates, infection tends to occur at older ages, resulting in higher susceptibility among adults than in temperate climates. Vaccine is used in United States, Austrailla, Canade, Costa Rica, Dominican republic, Germany, Mexico, Quatar, Spain, South Korea, Switezerland, United Arab Emirates and Urguary.
b. How many people has it affected?
most affected in US. over 1 million. Millions affected worldwide.
c. Is everyone equally vunerable, or does it target particular catagories of people? why?
(see question a) -people with weak immune systems. -Additionally, exposure to herpes zoster poses a risk for varicella infeciton in susceptable travelers although localized herpes zoster has been shown to be much less infectious than varicella. Travelers at higher risk for varicella disease are pregnent women without a history of disease or infeciton.
3. Impact
a. How has the disease impacted the course of history? Give an example.
The disease hasn't dramatically altered the course of history. Soon after the disease was discovered a vaccine was found. This disease didn't change the course of history.
b. How is the disease currently affeciting society? Now that we have a vaccine, the disease is much less prominent. People still get it as children, but now we know how to handle it, and it isnt a problem at all.
Sources Cited
"Historical Background." Virus. Web. 03 Mar. 2012. <http://virus.stanford.edu/herpes/History.html>. Andrei, G., and D. Topalis. "American Society for MicrobiologyJournal of Virology." Drug-Resistant Varicella-Zoster Virus Mutants. American Society for Microbiology, 20 Oct. 2011. Web. 03 Mar. 2012. <http://jvi.asm.org/content/86/5/2641.abstract>. Ehrlich, Steven D. "Varicella-zoster Virus." University of Maryland Medical Center. University of Maryland Medical Center, 2011. Web. 03 Mar. 2012. <http://www.umm.edu/altmed/articles/varicella-zoster-000080.htm>. Harriman, Kathleen Gilberto F. Chavez H., and Gilberto F. Chavez. "Chapter 3Infectious Diseases Related To Travel." Varicella (Chickenpox). Disease Control and Prevention, 1 July 2011. Web. 03 Mar. 2012. http://wwwnc.cdc.gov/travel/yellowbook/2012/chapter-3-infectious-diseases-related-to-travel/varicella-chickenpox.htm.